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It is probably wise to monitor the incidence of CDI following any change in a formularys antibiotic drug of choice. Several guidelines for antibiotic stewardship programs have been published (174,175,176). Additionally; it has been shown that the skin surfaces of patients with CDI diarrhea that resolved 2 weeks before is still contaminated with C.
One recommendation is to maintain contact precautions for 48?h after diarrhea ceases (178). Some institutions have implemented contact precautions for the duration of hospitalization as part of their infection control interventions for CDI (168).